Marmaduke destroyed or disturbed nearly every item in the house for reasons still at large. His owner-lady offers several hypotheses for the rampage that vary wildly in probability, failing to touch upon the most likely and obvious explanation (Marmaduke felt like it).

Marmaduke's fat, elderly neighbor has been huffing paint thinner again, which does not mix well with his Alzheimer's.

Marmaduke, in an exquisitely ironic bit of comical juxtaposition, is being disobedient on the way to obedience school.

Marmaduke's owner-man and owner-lady are not going to let him watch any more Fred Astaire movies, as they give him horrifically violent seizures.

Marmaduke is licking his owner-girl's mouth because it tastes like strawberries. Though it makes perfect sense for a dog to do this, I still find something about today's Marmaduke vaguely upsetting.